Butabarbital decreases effects of sufentanil SL by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Closely. Coadministration of CYP3A4 inducers may perhaps reduce sufentanil levels and efficacy, perhaps precipitating withdrawal syndrome in people which have made Bodily dependence to sufentanil. Discontinuation of concomitantly utilized CYP3A4 inducers cou... https://fredo874kgy5.blue-blogs.com/profile