Conolidine’s analgesic effects stem from its conversation with non-opioid pain pathways. As opposed to opioids, which bind to µ-opioid receptors within the central nervous method, conolidine modulates alternate molecular targets. A Science Innovations study identified that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, which regulates opioid peptide availability. https://sergionunfz.popup-blog.com/36676613/a-review-of-alternative-natural-pain-relief-to-replace-traditional-painkillers